Academia Open
Vol 9 No 1 (2024): June
Medicine

Efficacy of Calcium and Aspirin Intervention in Preeclampsia Prevention
Efektivitas Intervensi Kalsium dan Aspirin dalam Pencegahan Preeklampsia


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  • Ririn Retno Palupi*,
  • Siti Cholifah
Ririn Retno Palupi
Universitas Muhammaddiyah Sidoarjo, *
Siti Cholifah
Universitas Muhammadiyah Sidoarjo [https://ror.org/017hvgd88], Indonesia

(*) Corresponding Author
Picture in here are illustration from public domain image or provided by the author, as part of their works
DOI: https://doi.org/10.21070/acopen.9.2024.5943
Published May 17, 2024
Keywords
  • Preeclampsia,
  • Calcium,
  • Aspirin,
  • Pregnancy,
  • Prevention
How to Cite
Palupi, R. R., & Cholifah, S. (2024). Efficacy of Calcium and Aspirin Intervention in Preeclampsia Prevention. Academia Open, 9(1), 10.21070/acopen.9.2024.5943. https://doi.org/10.21070/acopen.9.2024.5943

Copyright (c) 2024 Ririn Retno Palupi, Siti Cholifah

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

This retrospective cohort study investigates the effectiveness of administering calcium and aspirin to pregnant women at risk of preeclampsia in reducing its incidence. Analyzing data from 143 pregnant women from January to December 2021, all subjects underwent preeclampsia risk screening. Chi-square analysis revealed a significant association (p < 0.001) between the consumption of calcium and aspirin and preeclampsia occurrence, with those receiving both supplements exhibiting a 3.8-fold decrease in incidence compared to those consuming calcium alone (OR: 3.8; 95% CI: 1.9-7.8). These findings underscore the potential of targeted supplementation with calcium and aspirin to mitigate preeclampsia risk, emphasizing the importance of early intervention in obstetric care. 

 

Highlight: 

  1. Early intervention reduces preeclampsia risk.
  2. Statistical significance: calcium and aspirin association with preeclampsia.
  3. Targeted supplementation improves maternal health.

 

Keyword:  Preeclampsia, Calcium, Aspirin, Pregnancy, Prevention

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